Activated vitamins are in a form that is readily available to be utilised by the body as a substrate in biochemical reactions immediately following ingestion. This means that they do not have to be broken down and manufactured by the body into a usable form as is the case with the inactive vitamins. This is beneficial if there is a problem with the process of digestion or if some enzymatic functions are lacking in some way. Activated vitamins are important co-factors in many body processes. In the case of Pyridoxal-5-Phosphate (P-5-P or activated B6) it is involved in more than 80% of reactions in the neurochemistry of the brain. The inactive form of P-5-P is Pyridoxine Hydrochloride.